The Silent Architect: How I Rebuilt My Energy by Decoding My Liver’s Cry for Help

Section 1: The Slow Fade to Grey: A Diagnosis in a World of Noise

Narrator’s Introduction & Core Struggle

The fade was insidious.

It wasn’t a sudden collapse but a slow, creeping erosion of color from my world.

As a creative director in a demanding field, my life was a carefully calibrated machine of deadlines, client pitches, and cross-country flights.

I thrived on the pressure, or so I told myself.

I ate what I thought was a “decent” diet—salads when I could, protein bars on the R.N. I exercised.

I slept seven, sometimes eight, hours a night.

Yet, a profound and unshakable fatigue had taken root deep in my bones.¹

It was a weariness that my morning espresso couldn’t dent and my afternoon cold brew couldn’t penetrate.

My work, once a source of electric energy, became a slog through a thick, cognitive fog.

Ideas that once sparked and crackled now felt distant and muffled.

I felt perpetually run-down, as if my internal batteries were corroded and could no longer hold a charge.¹

Friends would say, “You’re just burned out,” a common diagnosis in our hyper-productive culture.

But this felt different.

This wasn’t the satisfying exhaustion after a project well done; it was a systemic power failure.

The breaking point arrived not with a bang, but with a quiet moment of terrifying clarity.

Staring at a blank page, the deadline for a major campaign looming, I realized I couldn’t summon a single coherent thought.

The engine had stalled.

It was then I knew this wasn’t just a lifestyle issue I could “power through.” Something was fundamentally wrong.

I booked an appointment with my doctor, determined to move past the noise of well-meaning advice and get a real diagnosis.

The Unexpected Verdict

The doctor’s office was sterile, the questions routine.

But the follow-up call a week later was anything but.

My blood work had come back, and the results were a shock.

“Your liver enzymes are elevated,” my doctor said, her voice calm but firm.

She mentioned two acronyms I’d never heard before: ALT and AST.

Mine were high.

Alarmingly so.

She gently raised the possibility of Non-Alcoholic Fatty Liver Disease, or NAFLD, explaining that it was a silent epidemic affecting a staggering number of Americans—over 100 million, in fact.³

I was floored.

Liver problems? That was for heavy drinkers, wasn’t it? I was the picture of moderation.

The diagnosis didn’t fit my self-perception.

Yet, as I started to connect the dots, I saw how my story mirrored countless others.

Customer reviews for liver health supplements are filled with people who, like me, received an unexpected wake-up call in the form of a lab report showing “high liver values” or a “fatty liver” diagnosis.¹

One person shared their enzymes were at 170—a concrete, alarming number that resonated with my own fear.²

My initial confusion quickly curdled into frustration.

The internet, a supposed fount of wisdom, offered a cacophony of simplistic solutions.

“Detox your liver!” screamed the headlines.

“Try this 3-day juice cleanse!” suggested a wellness blog.

The market was saturated with products promising to “cleanse” and “flush” this vital organ.⁴

It all felt so superficial, so disconnected from the complex biological reality my doctor had described.

This wasn’t a stain to be scrubbed away; it was a complex system in distress.

I rejected the pseudoscience.

My path forward wouldn’t be a “cleanse”; it would be a forensic investigation.

Section 2: The Epiphany: The Liver is Not a Filter, It’s the Master Architect

Deconstructing the “Detox” Myth

My investigation began with a single-minded goal: to dismantle the “detox” myth.

The more I read from credible medical sources, the clearer it became that the concept of a “liver cleanse” is, at best, a marketing fiction and, at worst, potentially dangerous.

Hepatologists and medical experts from institutions like Johns Hopkins University do not recommend them, noting a lack of clinical data to support their efficacy.⁷

In fact, because the supplement industry is largely unregulated, some of these products can contain unlisted ingredients or contaminants that may actually cause liver harm.⁵

The very premise is flawed.

Your liver isn’t a passive filter like the one in your water pitcher, passively trapping gunk until it needs to be replaced or scrubbed.

It’s an incredibly powerful, dynamic organ that actively neutralizes and eliminates toxins on its own.¹⁰

The idea that it needs an external “detox” is a fundamental misunderstanding of its function.

My fatigue and elevated enzymes weren’t a sign that my liver was “dirty.” They were a cry for help.

My liver was overworked, under-equipped, and struggling to keep up with the demands of my modern life.

The “Master Architect” Analogy – A Paradigm Shift

This realization led me to my epiphany, a paradigm shift in how I viewed this incredible organ.

The liver is not a simple filter.

The liver is the body’s Master Architect.

Think about it.

This single organ is responsible for designing, building, powering, and maintaining the entire metropolis of your body.

It performs over 500 vital functions, a feat of biological engineering that makes the “filter” analogy seem almost insulting.¹²

• It’s a Materials Processing Plant: The Architect takes the raw materials from your diet—the carbohydrates, fats, and proteins—and masterfully converts them into the specific building blocks your body needs to function and grow.
• It’s a Central Power Station: It manages the city’s energy grid, producing glucose for immediate power and storing the excess as glycogen, ensuring a steady supply of fuel for every cell, tissue, and organ.
• It’s a Sophisticated Waste Management Facility: Far from being a passive trap, the Architect’s facility uses complex enzymatic processes to break down, neutralize, and package metabolic byproducts and environmental toxins for safe removal from the body. This is its natural detoxification process.¹³
• It’s a Chief Structural Engineer: The Architect synthesizes the vast majority of proteins circulating in your blood, including albumin, and the cholesterol needed to build and repair every cell membrane in your body.
• It’s a Regenerative Genius: Perhaps most remarkably, the Architect has the ability to rebuild itself. When damaged, it can regenerate its own tissue, a testament to its profound importance for survival.⁸

This new analogy changed everything.

An architect doesn’t need a “cleanse.” An architect needs a supply of premium-grade materials, a highly-skilled support crew, and a state-of-the-art toolkit to perform its complex jobs effectively.

My mission was no longer to find a “detox,” but to find the precise, scientifically-validated tools my body’s Master Architect was crying out for.

Section 3: The Blueprint for Renewal: A Forensic Investigation into the Architect’s Toolkit

Armed with my new “Master Architect” paradigm, I began a forensic investigation into the world of nutritional science.

I wasn’t looking for a magic bullet; I was looking for a blueprint.

I needed to identify the specific, high-quality “tools” and “materials” that could support my liver’s immense workload.

My research led me to a handful of powerful, clinically-studied compounds, the very ingredients that form the core of 1MD Nutrition’s LiverMD.

Each one plays a distinct, synergistic role in the Architect’s toolkit.

Part 1: The Cornerstone Material – The Problem of Bioavailability and the Phytosome Solution

The Flawed Foundation (Standard Milk Thistle)

My investigation started with the most famous liver herb on the planet: milk thistle.

For centuries, its extract, known as silymarin, has been used for liver ailments.6 However, my research quickly uncovered its Achilles’ heel: extremely poor bioavailability.

The primary active compound in milk thistle, silybin, is a powerful antioxidant, but it’s not easily absorbed by the human body.

It has low water solubility and is extensively metabolized and excreted before it can exert its full benefits.16 This critical flaw is why many large-scale clinical trials on standard milk thistle have yielded “equivocal results” or been inconclusive, leaving a cloud of uncertainty around its effectiveness.19 Using standard milk thistle is like giving your Master Architect a pile of high-grade sand but no cement to bind it into concrete.

The potential is there, but the material is unusable.

The Technological Breakthrough (Siliphos® Silybin Phytosome)

This is where modern science provides a brilliant solution.

My research led me to a cutting-edge delivery system called phytosome technology.

A phytosome is not merely an extract; it’s an elegant molecular complex.

In this process, the active plant compound (silybin) is bonded to a phospholipid—a fat molecule, like phosphatidylcholine, that is a primary component of our own cell membranes.21

The analogy is simple but powerful: imagine trying to mail a critical, water-soluble document in the rain.

On its own, it gets soaked and destroyed.

But if you place it inside a waterproof, lipid-based envelope, it arrives at its destination intact.

The phytosome is that envelope.

This structure allows the silybin to navigate the watery environment of the gut and then merge seamlessly with the lipid-based membranes of intestinal cells, dramatically increasing its absorption and delivery to the bloodstream and, ultimately, to the liver.²²

LiverMD utilizes a specific, patented version of this technology called Siliphos®.

Clinical data on Siliphos® is compelling, showing it possesses up to 10 times higher bioavailability than the generic milk thistle extracts found in most supplements.¹³

Human studies have confirmed that this enhanced absorption translates directly to higher concentrations of silybin reaching the liver, the target organ where it’s needed most.²¹

This isn’t just milk thistle; it’s milk thistle engineered for maximum impact.

It’s the high-performance, reinforced concrete the Architect needs to build and protect its most vital structures.

Part 2: The Master Antioxidant Crew – N-Acetyl Cysteine (NAC)

If Siliphos® is the advanced building material, N-Acetyl Cysteine (NAC) is the Architect’s elite, first-responder crew.

Many supplements boast of “antioxidant” properties, but NAC is in a class of its own.

Its primary power lies in its role as a direct precursor to glutathione, the most crucial and powerful antioxidant produced within our own cells.²⁷

Glutathione is the master detoxification agent and cleanup crew for the entire cellular metropolis.

It relentlessly neutralizes the free radicals and reactive oxygen species—the metabolic “exhaust fumes”—generated by the Architect’s tireless work of processing nutrients and toxins.

However, under the constant assault of a modern lifestyle—stress, environmental pollutants, processed foods—the body’s glutathione reserves can become severely depleted.

Supplementing with NAC is like sending in a fresh battalion of highly trained specialists to reinforce the front lines.

It provides the essential building block the body needs to replenish its glutathione stores, restoring its primary defense system against oxidative stress.

The power of NAC is not theoretical; it is a cornerstone of modern medicine.

It is the standard, FDA-approved antidote for acetaminophen overdose, a condition that causes catastrophic liver failure precisely by depleting glutathione stores.²⁷

Its ability to rescue the liver from such an acute crisis is a profound testament to its hepatoprotective power.

Furthermore, clinical studies have demonstrated its benefits in improving liver function in patients with NAFLD and other chronic liver conditions, making its inclusion in a comprehensive liver formula a mark of sophisticated, evidence-based design.²⁸

It was no surprise that discerning reviewers specifically highlighted the presence of NAC as a key reason for their confidence in the formula.¹

Part 3: The Universal Power Grid – Alpha-Lipoic Acid (ALA)

Every great city needs a reliable power grid and a versatile maintenance team that can work anywhere.

In the Architect’s toolkit, this role is filled by Alpha-Lipoic Acid (ALA).

What makes ALA so remarkable is its unique versatility.

It is an amphiphilic antioxidant, meaning it is soluble in both water and fat.²⁹

This allows it to exert its protective effects in every part of the cell: the aqueous interior (cytosol) and the lipid-based membranes that form the cell’s outer wall and enclose its organelles.

It’s the universal troubleshooter, capable of neutralizing threats on every front.

But ALA’s genius doesn’t stop there.

It is often called the “antioxidant of antioxidants” for its incredible ability to regenerate other key members of the antioxidant crew, including glutathione, Vitamin C, and Vitamin E.²⁹

When these other antioxidants neutralize a free radical, they become “spent” or oxidized.

ALA comes along and recharges them, returning them to active duty.

This creates a powerful, synergistic network of defense, where the entire system is stronger than the sum of its parts.

Critically for my own struggle with fatigue, ALA is also an essential cofactor for mitochondrial enzyme complexes that are vital for cellular energy production.²⁹

It directly supports the Architect’s power stations, helping to convert the food we eat into the ATP that fuels every single one of its projects.

Clinical evidence supports its role, with studies showing that ALA, especially when combined with Vitamin E, can significantly improve markers of liver health in patients with NAFLD and NASH.³⁴

Part 4: The Essential Support Staff & Raw Materials

A Master Architect also relies on specialized teams and a steady supply of essential raw materials.

• Cellular Protective Shielding (Vitamin E): LiverMD includes Vitamin E, but not just any form. It utilizes TocoGaia™, a full-spectrum tocotrienol and tocopherol complex.¹² Tocotrienols are potent, lipid-soluble forms of Vitamin E that excel at embedding themselves in cell membranes, acting as a protective shield against oxidative damage, a process known as lipid peroxidation.¹ This is the specialized armor plating that protects the Architect’s most critical structures from attack.
• Essential Minerals (Zinc & Selenium): These are the fundamental raw materials required for daily operations. Zinc is a crucial player in the body’s natural detoxification processes and supports healthy cellular function and division.¹ Selenium acts as a purifying mineral and is a structural component of key antioxidant enzymes, including glutathione peroxidase. It helps reduce oxidative stress and maintain the elasticity and integrity of liver tissue.¹ Together, they are the indispensable support staff ensuring the entire operation runs smoothly.

The Blueprint Summarized: The Master Architect’s Toolkit

My forensic investigation revealed not just a list of ingredients, but a cohesive, synergistic system.

Each component was chosen for a specific, evidence-based role, and they work together to create a virtuous cycle of support: NAC builds the antioxidant army, ALA recharges and redeploys it, Vitamin E armors the front lines, and Siliphos® reinforces the fortress walls, all while Zinc and Selenium provide the essential supplies.

Ingredient	Role in the Analogy	Core Scientific Function & Key Evidence
Siliphos® Milk Thistle	High-Performance Reinforcement Material	A patented silybin-phosphatidylcholine phytosome complex. Overcomes the poor bioavailability of standard milk thistle, delivering up to 10x more of the active compound to the liver to support cell health and function.13
N-Acetyl Cysteine (NAC)	The Master Antioxidant Crew	A direct precursor to glutathione, the body’s most powerful intracellular antioxidant. Replenishes this critical defense system to combat oxidative stress and support the liver’s natural detoxification processes.27
Alpha-Lipoic Acid (ALA)	The Universal Power Grid & Maintenance System	A unique water- and fat-soluble antioxidant. Protects all parts of the cell, regenerates other antioxidants like glutathione and Vitamin E, and supports mitochondrial energy production.29
Vitamin E (as TocoGaia™)	Cellular Protective Shielding	A full-spectrum tocotrienol/tocopherol complex. A potent lipid-soluble antioxidant that helps protect cell membranes from oxidative damage and supports healthy liver cell division.1
Zinc & Selenium	Essential Raw Materials & Support Staff	Critical minerals that function as cofactors for antioxidant enzymes and support the body’s natural detoxification pathways, promoting liver tissue integrity and healthy immune response.1

Section 4: The Rebuilding Phase: From Blueprint to a New Reality

Putting the Toolkit to Work

With my blueprint for renewal in hand, I felt a sense of confidence I hadn’t experienced since my diagnosis.

I wasn’t blindly trying a “cleanse”; I was strategically equipping my body’s Master Architect with the tools it needed to do its job.

I started taking LiverMD, following the recommended dosage of two easy-to-swallow capsules per day.¹

I knew from my research and from the experiences of others that this wasn’t going to be a “magic pill”.¹

The transformation was gradual, a slow dawn rather than a flick of a switch.

The first thing I noticed, after about two weeks, was a subtle shift in my afternoons.

The familiar 3 P.M. slump, where my brain would turn to static, began to recede.

I felt a bit more mental clarity, a touch more focus.¹

Waking up in the morning became easier; the feeling of being pinned to the mattress by an invisible weight started to lift.¹

These small changes began to compound.

Over the next month, the persistent brain fog that had clouded my creativity started to dissipate.

The bone-deep fatigue was replaced by a sense of sustained, stable energy throughout the day.

I felt a renewed sense of vitality, a feeling of well-being that I had almost forgotten was possible.

My experience echoed those of many others who reported feeling more energized and simply “better overall” after consistently using the product.¹

The Ultimate Validation: The Follow-Up Test

The true climax of my journey came three months later, back in the familiar, sterile environment of the lab for a follow-up blood test.

The anxiety was palpable as I waited for the results.

When the call came, the relief was immense.

My doctor’s voice was bright, almost celebratory.

“Your liver enzymes,” she said, “are back in the normal range.”

The numbers on the page were the ultimate validation.

It was objective, undeniable proof that my forensic investigation and subsequent actions had worked.

This moment was the culmination of my entire journey, mirroring the powerful story of the user whose enzymes had plummeted from a dangerous 170 down to a healthy 85.²

Another user reported that their doctor was so impressed with their improved blood work that they planned to recommend the supplement to other patients.²

It is crucial to state, however, that LiverMD was a powerful catalyst, not a panacea.

My journey taught me that you cannot supplement your way out of a bad lifestyle.

Armed with my new understanding of the Architect’s needs, I made conscious changes.

I reduced my intake of processed foods and sugars and focused on antioxidant-rich whole foods.

I committed to regular exercise.

The supplement was the critical toolkit that enabled my liver to repair and regenerate, but the commitment to a healthier lifestyle was the foundation upon which that rebuilding took place.¹

Section 5: Building Your Own Foundation of Trust in a Skeptical World

Addressing the Elephant in the Room

My journey forced me to confront a difficult truth: the dietary supplement industry is a wild west, fraught with unsubstantiated claims, a lack of regulation, and products that can be ineffective or even harmful.⁵

This reality breeds a healthy and justified skepticism in any discerning consumer.

We are right to be cautious.

We are right to demand proof.

The 1MD Nutrition Difference: A Framework for Trust

So, how does one navigate this landscape? My investigation into LiverMD also became an investigation into its creator, 1MD Nutrition.

I discovered a company seemingly built from the ground up to counteract this very skepticism.

Their approach provided me with a framework for what a trustworthy brand should look like, a model built on what they call a “trilogy approach” to health.³⁸

1. Physician-Formulated: The formulas are not developed in a marketing boardroom. They are developed in collaboration with board-certified physicians who bring deep medical expertise to the table. LiverMD, for instance, is backed by Dr. David Kahana, a physician triple-board-certified in Pediatrics, Gastroenterology, and as a Physician Nutrition Specialist.¹² This commitment to medical oversight ensures the formulas are grounded in real-world clinical understanding.³
2. Clinically-Effective Dosages: This was a critical point for me. So many companies engage in “fairy dusting”—including a trendy ingredient in a minuscule amount just to put it on the label. 1MD Nutrition’s philosophy is to use ingredients at the same dosages that showed results in the peer-reviewed clinical trials.³⁸ This commitment to effective dosing means the product isn’t just based on science; it’s formulated to replicate the success of that science.
3. Commitment to Quality & Transparency: In an industry where you often don’t know what you’re getting, verifiable quality control is paramount. 1MD Nutrition manufactures its products in GMP-certified (Good Manufacturing Practices) facilities.³⁸ More importantly, they commit to third-party testing.⁴⁰ This means an independent lab verifies that what’s on the label is actually in the bottle and that the product is free from contaminants. This is a voluntary step that demonstrates a profound commitment to safety and quality, providing consumers with the confidence they deserve.⁴¹

The Call to Action: Become Your Own Health Architect

My journey began with a diagnosis and ended with a new philosophy.

I learned that my health is not a passive state but an active project.

This article is not a prescription.

It is the story of my investigation, a blueprint of my own discovery.

The final and most important call to action is not simply to buy a product, but to adopt the mindset of an architect for your own health.

Be proactive.

Be relentlessly curious.

Reject simplistic myths and demand rigorous evidence.

Partner with your healthcare provider to understand your body’s unique needs.

You are the Master Architect of your own well-being.

Arm yourself with knowledge, demand transparency from the companies you support, and choose your tools wisely.

Your health is the most magnificent structure you will ever build.

Furnish it with the very best.

Works cited

1. Customer reviews for 1MD Nutrition LiverMD – Liver Cleanse Supplement | Siliphos Milk Thistle Extract – Highly Bioavailable, Clinically Studied for Liver Detox | 60 Capsules | Walmart.com, accessed on August 9, 2025, https://www.walmart.com/reviews/product/789457217
2. Customer reviews for 1MD Nutrition LiverMD – Liver Cleanse Supplement | Siliphos Milk Thistle Extract – Highly Bioavailable, Clinically Studied for Liver Detox | 60 Capsules | Walmart.com, accessed on August 9, 2025, https://www.walmart.com/reviews/product/435225301
3. Physician-Formulated Solutions from 1MD Nutrition Target Major …, accessed on August 9, 2025, https://www.nutraceuticalsworld.com/physician-formulated-solutions-from-1md-nutrition-target-major-health-concerns/
4. 1 Md Nutrition – Walmart, accessed on August 9, 2025, https://www.walmart.com/c/kp/1-md-nutrition
5. The Best Liver Supplements to Support Your Overall Health – GoodRx, accessed on August 9, 2025, https://www.goodrx.com/health-topic/liver/best-liver-supplements
6. What You Should Know Before Taking Liver Supplements – Healthline, accessed on August 9, 2025, https://www.healthline.com/health/liver-supplement
7. Detoxing Your Liver: Fact Versus Fiction | Johns Hopkins Medicine, accessed on August 9, 2025, https://www.hopkinsmedicine.org/health/wellness-and-prevention/detoxing-your-liver-fact-versus-fiction
8. Can Supplements Damage Your Liver? – Health Matters – NewYork-Presbyterian, accessed on August 9, 2025, https://healthmatters.nyp.org/can-supplements-damage-your-liver/
9. 6 Popular Supplements That Can Damage Your Liver – AARP, accessed on August 9, 2025, https://www.aarp.org/health/drugs-supplements/supplements-that-can-harm-liver/
10. Do You Need Liver Cleanse Supplements? – UNC Health Talk, accessed on August 9, 2025, https://healthtalk.unchealthcare.org/do-you-need-liver-cleanse-supplements/
11. Popular liver supplements lack data supporting efficacy, study shows | MDedge, accessed on August 9, 2025, https://www.mdedge.com/content/popular-liver-supplements-lack-data-supporting-efficacy-study-shows
12. 5 essential doctor-recommended nutrients to support your liver health – St. Louis American, accessed on August 9, 2025, https://www.stlamerican.com/online-features/health-and-wellness/5-essential-doctor-recommended-nutrients-to-support-your-liver-health/
13. 1MD Nutrition LiverMD – 60 Capsules Liver Support Supplement for Liver Support | eBay, accessed on August 9, 2025, https://www.ebay.com/itm/226857986065
14. Milk Thistle: Benefits and Side Effects – WebMD, accessed on August 9, 2025, https://www.webmd.com/fatty-liver-disease/milk-thistle-benefits-and-side-effects
15. MILK THISTLE: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews, accessed on August 9, 2025, https://www.webmd.com/vitamins/ai/ingredientmono-138/milk-thistle
16. Silybin and the liver: From basic research to clinical practice – PMC, accessed on August 9, 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC3098397/
17. Silybin as Siliphos® Partially Protects against Experimental Liver… | Download Scientific Diagram – ResearchGate, accessed on August 9, 2025, https://www.researchgate.net/figure/Silybin-as-SiliphosR-Partially-Protects-against-Experimental-Liver-Damage-from-Carbon_fig2_7599396
18. Summary of Health Canada’s safety assessment of milk thistle seed extract for use as a supplemental ingredient, accessed on August 9, 2025, https://www.canada.ca/en/health-canada/services/food-nutrition/legislation-guidelines/acts-regulations/notices-proposal-notices-modification/list-permitted-supplemental-ingredients-enable-use-milk-thistle-seed-extract-silymarin/document.html
19. Milk Thistle Uses, Benefits & Dosage – Drugs.com, accessed on August 9, 2025, https://www.drugs.com/npp/milk-thistle.html
20. Milk Thistle | AAFP, accessed on August 9, 2025, https://www.aafp.org/pubs/afp/issues/2005/1001/p1285.html
21. (PDF) A review of the bioavailability and clinical efficacy of milk thistle phytosome: A silybin-phosphatidylcholine complex (Siliphos®) – ResearchGate, accessed on August 9, 2025, https://www.researchgate.net/publication/7599396_A_review_of_the_bioavailability_and_clinical_efficacy_of_milk_thistle_phytosome_A_silybin-phosphatidylcholine_complex_SiliphosR
22. A Review on Phytosome Technology as a Novel Approach to Improve The Bioavailability of Nutraceuticals – ResearchGate, accessed on August 9, 2025, https://www.researchgate.net/publication/232244782_A_Review_on_Phytosome_Technology_as_a_Novel_Approach_to_Improve_The_Bioavailability_of_Nutraceuticals
23. Phytosome – Knowledge and References – Taylor & Francis, accessed on August 9, 2025, https://taylorandfrancis.com/knowledge/Medicine_and_healthcare/Medical_genetics/Phytosome/
24. Phytosome Technology: A Novel Breakthrough for the Health Challenges – PMC, accessed on August 9, 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC11439478/
25. Unlocking the potential of phytosomes: a review of formulation techniques, evaluation methods, and emerging applications – ScienceOpen, accessed on August 9, 2025, https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0055
26. 1MD LiverMD – Liver Support Supplement | Siliphos Milk Thistle Extract 60 Caps | eBay, accessed on August 9, 2025, https://www.ebay.com/itm/396616024667
27. Acetylcysteine – LiverTox – NCBI Bookshelf, accessed on August 9, 2025, https://www.ncbi.nlm.nih.gov/books/NBK548401/
28. N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature – PubMed, accessed on August 9, 2025, https://pubmed.ncbi.nlm.nih.gov/33339155/
29. Therapeutic Potential of Alpha-Lipoic Acid: Unraveling Its Role in Oxidative Stress and Inflammatory Conditions – MDPI, accessed on August 9, 2025, https://www.mdpi.com/1467-3045/47/5/322
30. N-acetyl cysteine versus standard of care for non-acetaminophen induced acute liver injury: a systematic review and meta-analysis – PubMed, accessed on August 9, 2025, https://pubmed.ncbi.nlm.nih.gov/33722689/
31. N-Acetylcysteine Improves Liver Function in Patients with Non-Alcoholic Fatty Liver Disease, accessed on August 9, 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC3270338/
32. The effects of N-acetylcysteine on hepatic, hematologic, and renal parameters in cirrhotic patients: a randomized controlled trial – PubMed, accessed on August 9, 2025, https://pubmed.ncbi.nlm.nih.gov/38313355/
33. Alpha-Lipoic Acid: Biological Mechanisms and Health Benefits – MDPI, accessed on August 9, 2025, https://www.mdpi.com/2076-3921/13/10/1228
34. Effect of Vitamin E and Alpha Lipoic Acid in Nonalcoholic Fatty Liver Disease: A Randomized, Placebo-Controlled, Open-Label, Prospective Clinical Trial (VAIN Trial), accessed on August 9, 2025, https://www.scirp.org/journal/paperinformation?paperid=45959
35. Effect of alpha-lipoic acid and Silybum marianum supplementation with a Mediterranean diet on metabolic dysfunction-associated steatosis – Baishideng Publishing Group, accessed on August 9, 2025, https://www.wjgnet.com/1948-5182/full/v17/i1/101704.htm
36. www.walmart.com, accessed on August 9, 2025, https://www.walmart.com/reviews/product/789457217#:~:text=1MD%20LiverMD%20Liver%20Cleanse%20Supplement,-janecaboto&text=The%20pills%20contain%20Vitamin%20E,363%25%20of%20daily%20recommended%20selenium.
37. Milk Thistle (PDQ®) – National Cancer Institute, accessed on August 9, 2025, https://www.cancer.gov/about-cancer/treatment/cam/hp/milk-thistle-pdq
38. 1MD REVOLUTIONIZING HEALTHCARE | New York Lifestyles Magazine, accessed on August 9, 2025, https://newyorklifestylesmagazine.com/articles/2025/01/fe01.html
39. Doron Kahana, M.D. – National Board of Physician Nutrition Specialists, accessed on August 9, 2025, https://nbpns.org/certified_physician/doron-kahana-m-d/
40. 1MD Nutrition LiverMD – Liver Support Supplement | Jordan | Ubuy, accessed on August 9, 2025, https://www.ubuy.com.jo/en/product/8M224PMLC-1md-livermd-liver-support-supplement-siliphos-milk-thistle-extract-highly-bioavailable-for-liver-support-60-capsules-2-pack
41. How to Tell if Your Supplements are Third-Party Certified And Why You Should Care, accessed on August 9, 2025, https://certifications.nutrasource.ca/blog/how-to-tell-if-your-supplements-are-third-party-certified-and-why-you-should-care
42. Independent Verification & Testing: How to Know If Your Supplements Are Safe, accessed on August 9, 2025, https://www.verywellfit.com/supplement-testing-8303184
43. Third-Party Testing for Supplements: Everything You Need to Know, accessed on August 9, 2025, https://ultraversesupplements.com/third-party-testing-for-supplements